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    October 31

    Still losing weight

    This morning, I was down to 54 kilos. That's still a BMI of 19.6, but I can't understand why I'm losing weight.
    October 30

    Aches and pains

    My ribs hurt. Especially on the lower left side, but also on the back, and this morning when I went swimming, I had a bad twinge on the upper right. It's kind of achey, not sharp. More like muscle aches.
    October 29

    Cortisol

    Got this response re: Hyperglycemia from the Yahoo! list:
     
    Cortisol and blood sugar:
    In this link, scroll down the page past those ads and read.
    http://www.faqs.org/health/topics/16/Cortisol-tests.html
    There are many others on this sbjct, though I am not saying that that is exactly where the higher blood sugar and weight loss are coming from.
    With the lower weight, you wouldn't fit the "atypical" profile, but then we're all very different. I'm thinking there's a possibility that you MAY
    have a lower cortisol, where it can't help to put blood sugar into your cells, yet your insulin may be stimulated to the point of an insulin
    overload? Don't know. Have you had a fasting insulin test (not the fasting blood sugar, that one is routine).

    No, I haven't had a fasting insulin test. And as I understand the link, low cortisol would lower blood sugar. Cortisol inhibits insulin, so low cortisol levels would mean that there would be too much insulin, and thus too low blood sugar. But if the cortisol level were too high, then the insulin production would be decreased, meaning high blood sugar. However, high cortisol levels are associated with hyperthyroidism, not hypo, and my lab results show a low functioning thyroid.

    October 27

    Another good Thyroid site

    Referred to this site from the Yahoo! list. Guess they're good for something after all. (Although the referral was in response to someone else's query, not mine.)
     
     
    Found this one on my own. Hasn't been updated in a while, but contains a huge list of potentially helpful links on thyroid issues.
     

    Getting help, helping myself

    I have an appointment with a nutritionist on November 6th. I want to get a diet plan that will help me to maintain my weight (not lose any more weight), discourage the development of diabetes, and reduce the amount of protein from animal sources. I don't want to go Vegan, but I don't like eating meat much and would like to cut it out altogether. May need to stay on iron supplements permanently. I also don't like eating cheese and eggs all the time, I find them fatty. Protein substitutes like Cornaturn and Quorn are expensive. Legumes may be a viable option. Had a delicious dhal dish today. Smile
     
    I have an appointment with a thyroid specialist on November 7th. They want to do an ultrasound scan to determine the exact size, shape, and position of the thyroid. Both to absolutely rule out a tumor, and as a control for later developments, in case enlargement or nodules were to occur.
     
    I've joined a Yahoo!Groups Thyroid mailing list. So far, they haven't been very helpful. I asked a question about hyperglycemia and Hashimoto's, and one person responded:
     
    Yes! I had it badly... I would faint if I didn't eat every hour and a
    half. The trick is to eat less and more often, with or without
    Hashis', so the body doesn't go into starvation mode - in starvation
    mode the body thinks it needs to store, not burn fat. That's when
    your metabolism suddenly crashes. Make sure to eat "quality" protein
    every time you eat. If you eat too many carbs the cycle will
    continue, the metabolism will worsen, and weight will continue to
    climb.

    That sounds an awful lot like hypoglycemia to me. Think she was confused. No one else responded. I also asked a question about soy products, and asked for a source for the claim that soy products were bad for Hashimoto's, but only got this response:
     
    Well I believe that this is true. After researching
    and reading many posts. I have figured out that my
    daughter should not be eating or drinking soy
    products. Amber is now off all soy as well as products
    made with soy. Her TSH levels and t3 and t4 are fine
    now. She is feeling so much better. She is not tired
    anymore and does not seem to get the brain fog that
    she always has had. Just being a teenager is hard
    enough as it is and then through in hashimoto's on top
    of it.
     
    Well, that could be anything. The girl, Amber, could have an allergy. This is by no means proof that the soy products exacerbated her Hashimoto's, or interfered with the absorption of her medication. And no reference to any published studies or authoritative sources.
     
     

    Soy and thyroid

    Interactions of soy products and thyroid medication:

     

    http://www.soymilkquick.com/thyroiddisease.asp

     

    Excerpts: Many foods contain goitrogens, compounds that interfere with thyroid function (and in extreme cases can cause an enlarged thyroid, called a goiter). Along with soyfoods, millet, cruciferous vegetables and other foods contain goitrogens. Generally, these foods cause problems only in areas where iodine intake is low since this mineral is important for thyroid function. The effects of iodine deficiency can be made worse if the diet is high in goitrogens.

     

    Maybe you have an existing medical condition and you're concerned about your soy consumption. Or perhaps, you've heard rumours about the effects of soy on your thyroid. Well, from the detailed research we've tracked down, you don't have to worry about eating whole soyfoods each day -- although some on medication for their thyroid have been recommended to avoid the soy at the same time as taking their medication.

     

    Soy and some other dietary supplements can interfere with the absorption and action of thyroid medications. However, they do not damage the thyroid in and of itself. (Yes, I realize that site is published by the soy industry. That doesn't necessarily mean that what they say isn't true.)

     

    Other sites say that soy does damage the thyroid. Soy contains isoflavones, which are chemically similar to hormones and can worsen an existing thyroid problem. See for example here:

     

    http://thyroid.about.com/cs/soyinfo/a/soy.htm

    October 24

    How It Began

    Shortly before Easter, I went to the doctor for something minor; I don't even remember what, probably a cold or something. As it had been a long time since my last blood sugar test and I had a history of gestational diabetes, the doctor suggested checking my long-term blood glucose (HbA1c). The results showed 5.9 mM (106 mg/dl), which is on the high end of normal (up to 6.0 is considered normal). At the same time, the doctor suggested that as I am getting close to 40, I come in for a full check-up. In the meantime, I should try to cut out sweets in order to bring my blood glucose levels down, but that there was no need for immediate treatment or followups.
     
    (Four months later...)
     
    I returned for the full check-up and a round of fasting blood tests. This time, the HbA1c was 6.4, clearly abnormal. I was shocked! I had cut out every conceivable sweet, read labels to avoid hidden sugars, continued my exercise routine and maintained my weight. Clearly, there was something wrong. I should return in two weeks for the results of the rest of the tests. I asked at this point to be referred to a nutritionist, but the doctor said that wasn't necessary. I argued that obviously, I had been doing something wrong with the diet, but she wanted to await the results of the rest of the tests. Unhappy, but unable to insist, I left and re-thought my menu.
     
    I have to say that during those months, I was compensating the sugars with starchy foods. I didn't monitor my total carbohydrate intake. I ate as much bread, pasta, muesli, and potatoes as I felt like. I snacked on foods such as potato chips, crackers, and dry fruits. Now, I did this on purpose, figuring that a normal (i.e. non-diabetic) person would be able to eat normal amounts of these foods and not show abnormally elevated blood glucose levels. I am 166 cm (65 inches) and at that point was around 58 kilos (127 pounds). So I was by no means overweight, and was certainly not overeating. The results of the blood test showed, to me, that I was unable to handle an unregulated carbohydrate intake, and that was really a blow to me. I was much too young to be developing Type 2 diabetes! I asked for a prescription for blood glucose test strips for my home blood glucose monitor (which I still had from my pregnancy, 7 years earlier). The doctor did not want to give one to me, saying that it wasn't necessary and would only make me nervous. I was beginning not to like this doctor! This time, I insisted, and she grudgingly wrote out the prescription.
     
    So I went back home and dug out my information on the Diabetic Exchange Diet, put new batteries into my blood glucose monitor, and started counting carbs. I calculated that I should use a 2000-calorie-a-day diet, which sounded really high to me, but it's based on 16 calories per pound of body weight, which is what insulin-dependent diabetics are recommended to eat. I found the following 1900-calorie-a-day diet:
     
  • 9 starch/bread exchanges
  • 6 fruit exchanges
  • 2 vegetable exchanges
  • 2 milk/dairy exchanges (1% milk)
  • 7 meat/protein exchanges (lean-medium fat)
  • 4 fat exchanges 
     
    From my previous experience with the Exchange Diet, I decided to ignore the fats and just use whatever oil, butter, mayonnaise, and peanut butter I wanted. I had lost weight on the Exchange Diet during my pregnancy and had to add fats anyway, so I wasn't really going to run into the problem of having too much fat. I divided the exchanges like this:
     
    Breakfast: 1 starch, 1 fruit, 1 milk
     
    Snack: 2 starch, 1 protein
     
    Lunch: 2 starch, 2 protein, 1 veg, 2 fruit
     
    Snack: 2 fruit, 1 starch, 1 milk
     
    Dinner: 2 starch, 3 protein, 1 veg
     
    Snack: 1 starch, 1 protein, 1 fruit
     
    That's a lot of food! I usually couldn't eat that much every day. And it began to show. I started losing weight. I was down to 56 kilos (122 pounds) when I returned to the doctor. 
     
    When I went back to the doctor for the rest of the blood test results, I was totally unprepared for what she told me. She said I had developed Hashimoto's Disease, also known as autoimmune thyroiditis. Basically, my immune system was destroying my thyroid gland, and there was nothing that could be done about it. It is not a life-threatening condition, and easily treated nowadays with hormone replacement therapy. If untreated, she told me, the symptoms are general lethargy, dry skin, irregular menstrual periods, depression, feeling cold, weight gain, hair loss, and short-term memory problems. I did not feel that I had any of those symptoms, except for the irregular menstrual periods, but I have had those my entire life; this was not a new development. The doctor said I did not need to begin with the hormones yet, that my thyroid hormone levels were not that low yet. She also said that the Hashimoto's was probably what caused the abnormal blood glucose test results, and not diabetes at all, but that, nevertheless, I should continue with the diabetic diet, and come back in two months to check the thyroid hormone levels.
     
    She did not give me any of the test results, did not explain how the diagnosis was arrived at, and despite the fact that I'd dropped down below my usual weight, refused to give me a referral to a nutritionist. She did not explain how the Hashimoto's could have caused the abnormal blood glucose result. I guess I was in too much shock over the diagnosis to ask any questions or form and cohesive arguments at that point.
     
    I went home and of course immediately typed in Hashimoto's Disease into the computer, and found out a lot more. I did find that autoimmune thyroiditis is often associated with Type 1 diabetes (which is also an autoimmune disease), but I did not find any correlation between Hashimoto's and Type 2 diabetes or hyperglycemia. 
     
    After the diagnosis, I continued to lose weight. I was down to 55 kilos (120 pounds). I called the doctor's office and told the office assistant that something was seriously wrong, either with me, or with the diet, and I wanted to see the other doctor in the practice, Dr. Sutter, as soon as I got back from vacation (which we had already booked).
     
    The first Monday after we got back, I went to see Dr. Sutter. I had a big list of questions, and he started off answering one right away by telling me I didn't have diabetes (I am still not sure about this, though; I am considering the possibility that it might be Type 1.5, slow-developing autoimmune diabetes, also called LADA). Then he explained all of the lab results to me. Here they are:
     
    Iron            5.8      (normal 6.6-26) umol/l
    Ferritin        3      (normal 10-310) um/l
    Protein      79.3      (normal 63-82) g/l
    Vitamin B12 209      (normal 156-672 pmol/l
    Folic acid   37.6      (normal 2.5-45-4 nmol/l
    TSH basal  30.18      (normal 0.35-4.5) mU/l
    Free Thyroxin (FT4)   8.4      (normal 10.3-21.9)
    Free Trijodthyronin (FT3)   3.81      (normal 3.08-6.47)
    Anti-Microsomal-AK (TPO)   >1300      (normal <60)
    Anti-Thyroglobulin (TG)   81      (normal <60)
    TSI/TRAK quantitative   0.5      (normal <1.0) U/l
     
    The diagnosis of Hashimoto's is based on the TSH and the Anti-Microsomal-AK values, which are both massively increased. The TSH is the Thyroid Stimulating Hormone. The fact that it is so high means that my thyroid is putting barely anything out at all, and my body is trying to force it into overdrive. In fact, it has forced it into overdrive. And even being pushed to its limit and beyond, my thyroid is only able to produce a bare minumum of FT3 and FT4 (the thyroid hormones necessary to metabolism). The Anti-TPO and Anti-TG values are antibodies against the thyroid. The fact that the values are so high, especially the TPO, means that my body is launching a massive attack on the thyroid gland. Eventually, it will be destroyed.
     
    Just found this nice page on Thyroiditis: http://www.emedicine.com/med/topic949.htm
     
    Dr. Sutter gave me the references to the thyroid specialist and the nutritionist. He suggested that I get a blood sugar monitor and check my morning and evening blood sugar occasionally. (Plus point for him for the thought, but minus point for not noticing in my file that I already have one, and that his practice partner had already prescribed the test strips.)
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